1. Chemical Sensors, Nanoparticles, and Microfluidics for Medical Diagnostics
A major research focus of the Wang group is the development of portable, wearable, and microfluidic chemical sensors for health monitoring and disease diagnosis outside of hospital settings. Current efforts include the design of ionophore-based ion-selective electrodes/optodes for calibration-free ion measurements and fluorescent sensing platforms in droplet microfluidics for continuous monitoring of critical care chemicals/biochemicals.
Sponsors: NIH-NIBIB (R01, R21), NIH-NCI (joint R01), JDRF, Orphan Disease Center (Phase I, Phase II), Calcilytix, Virginia Innovation Partnership Corporation, VCU (Breakthroughs Fund), VCU TechTransfer (Commercialization Fund), Massey Comprehensive Cancer Center.
VCU News: https://news.vcu.edu/article/home-calcium-monitoring-device
Selected to inaugural Startup Accelerator program:
Highlighted in VCU Annual Report:
https://vcu.us20.list-manage.com/track/click?u=d02688ee1f2d95b8daf9c1784&id=84185889f2&e=989fc052cd
(Angew. Chem. 2019, 58, 8092; Anal. Chem. 2021, 93, 40, 13694)
2. Nitric Oxide-Releasing Solutions, Nanocarriers, and Bioimplants
Nitric oxide is a natural molecule with potent anti-thrombotic, bactericidal, anti-inflammatory, and pro-angiogenic properties. We are developing various nitric oxide release/generation strategies to reduce foreign body reactions and infections to biomedical implants like sensors, catheters, and cannulas. One focus is to develop liquid formulations that generate nitric oxide with precisely controlled durations and concentrations.
Sponsors: NIH-NHLBI (R01), CHRB (Commonwealth Health Research Board), VCU-CCTR, VCU TechTransfer (Commercialization Fund).
VCU News:
VCU TechTransfer News:
https://innovationgateway.vcu.edu/news/featuredstories/when-it-comes-to-no-one-inventor-says-yes/
